Immunohematology Boot Camp: Duffy

Please note: AABB reserves the right to make updates to this program.

Live Program Date: Wednesday, August 22, 2018 - On-Demand Available

Master Program Number: 18EL-352 (see program format numbers below under Registration)

Educational Track: Technical/Clinical
Topic: Transfusion Medicine
Intended Audience: Immunohematology Reference Labs (IRL’s), Laboratory Staff, Medical Directors, Physicians, Resident/Fellow, Students (MD, MT, SBB), Technologist, Managers/Supervisors
Teaching Level: Basic to Intermediate

Director/Moderator: Kerry L. O’Brien, MD, Medical Director Blood Bank, Beth Israel Deaconess Medical Center, Boston, MA
Speaker: Jayanna Slayten, MS, MT(ASCP) SBB, IUH Blood Bank Supervisor and UTMB SBB Teaching Assistant, Indiana University Health Transfusion Service, Indianapolis, IN

Learning Objectives

After participating in this educational activity, participants should be able to:

  • Describe and explain the genetic background of the Duffy Blood group system and the associated phenotypes. 
  • Highlight the role of the Duffy glycoprotein in malarial infections and as a chemokine receptor.
  • Explain the significance of the GATA promoter region mutation as it relates to individuals who appear Fy(a-b-).
  • Describe the clinical significance of antibody formation to the Duffy antigens in clinical practice.
  • Apply knowledge gained from the lecture to RBC antibody case studies related to the Duffy Blood Group. 

Program Description

This program will describe the structure, distribution and clinical significance of the Duffy antigens. The role of the DARC glycoprotein in certain disease/infectious states will also be discussed. Antibodies to Duffy antigens are usually clinically significant and have been reported to cause hemolytic disease of the fetus and newborn.


   Program #
Single Viewer: On-Demand Register18EL-352-4035
Group Viewing: On-Demand Register18EL-352-8035

Continuing Education Credit

AABB designates both the live and on-demand version of this eCast each eligible for 1 continuing education credits/contact hours for Physicians, General Participation, California Nurse, California Lab Personnel and Florida Lab Personnel. The number and type of credits awarded for this program (both live and on-demand) was determined by the program duration. For more information on each credit type please visit our Continuing Education Credits webpage.

Disclosures for the planners of this event can be found here. Disclosures for the program faculty are provided at the beginning of the program.

Speaker Biography

Jayanna Slayten has been a dedicated blood banker since 1996.  She completed her BS in Biology at Georgetown College in Georgetown, KY then went to University of Kentucky for her Medical Technology training.  After starting her career at the VA in Indianapolis, she pursued her Specialist in Blood Bank and attained her Masters in Blood Transfusion Medicine from the University of Cincinnati.  Jay returned to Indianapolis as an IRL Manager at the Indiana Blood Center for 18 years.  Since 2016, Jay has returned to the Transfusion Service and became the supervisor of the Indiana University Health Transfusion Service in 2017. 

Throughout her career in Transfusion Medicine Jay has been an educator.  She is active in the ISABB, ASCP and AABB serving on many committees and participating in education events including the AABB Annual Meeting where she is the director of the annual BB/SBB Exam Review.  Jay was the Education Coordinator of the IBC SBB Program from 2005-2016, and now continues to work with SBB Students as the Teaching Assistant for the University of Texas Medical Branch SBB Program.