Transfusion-Associated Circulatory Overload (TACO) Risk Mitigation - What Can Hospital Blood Banks Do to Reduce Risk?

Please note: AABB reserves the right to make updates to this program.

Live Program: Wednesday, May 8, 2019 - On-Demand Available

Master Program Number: 19EL-449 (see program format numbers below under Registration)

Educational Track: Technical/Clinical
Topic: Transfusion Medicine
Intended Audience: Hospitals, Hospital Blood Banks, Immunohematology Reference Labs (IRL’s), Laboratory Staff, Medical Directors, Nurses, Physicians, Research Scientists, Resident/Fellow, Scientists, Students (MD, MT, SBB), Technologists, Transfusion Safety Officers
Teaching Level: Intermediate

Director: Nancy M. Dunbar, MD, Associate Professor of Pathology and Laboratory Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH
Moderator: April D. Hord, BB(ASCP)SBB, M.Ed., IRL Technical Trainer, American Red Cross, Richmond, VA
Speakers: Michael F. Murphy, MD, FRCP, FRCPath, FFPath, Consultant Hematologist, John Radcliffe Hospital, Oxford, United Kingdom; Alexander Vlaar, MD, PhD, MBA, Physician, Academisch Medisch Centrum - Universiteit van Amsterdam, Amsterdam, Netherlands

Learning Objectives

After participating in this educational activity, participants should be able to:

  • Review of the diagnosis of Transfusion Associated Circulatory Overload (TACO) and its differentiation from other pulmonary events like TRALI.
  • Identify recognized risk factors for the development of Transfusion Associated Circulatory Overload (TACO).
  • List strategies to reduce risk for Transfusion Associated Circulatory Overload (TACO) in patients requiring transfusion.
  • Describe how hospital transfusion services can help mitigate risk and list ways AABB accredited institutions are complying with AABB Standard 5.19.7.

Program Description

Transfusion Associated Circulatory Overload (TACO) is a common cause of transfusion-related morbidity and mortality. AABB Standard 5.19.7 (31st Edition) states, “the blood bank/transfusion service shall have a policy for responding to requests for products for patients identified by the ordering physician or other authorized health professional as being at increased risk for TACO”. In this program, participants will learn risk factors for the development of TACO and learn how hospital transfusion services mitigate risk for this complication.


   Program #
Single Viewer: On-Demand Register19EL-449-4035
Group Viewing: On-Demand Register19EL-449-8035

Continuing Education Credit

AABB designates both the live and on-demand version of this eCast each to be eligible for 1.0 continuing education credits/contact hours for Physicians, California Nurse, California Lab Personnel, Florida Lab Personnel and General Participation credit. The number and type of credits awarded for this program (both live and on-demand) was determined by the program duration. For more information on each credit type please visit our Continuing Education Credits webpage.

Disclosures for the planners of this event can be found here. Disclosures for the program faculty are provided at the beginning of the program.

Speaker Biographies

Mike Murphy is Professor of Transfusion Medicine at the University of Oxford and is Consultant Haematologist for NHS Blood & Transplant (NHSBT) and the Oxford University Hospitals NHS Foundation Trust. He provides the leadership for the hospital transfusion and immunohaematology services for the Oxford University Hospitals. He is a recipient of the British Blood Transfusion Society's Kenneth Goldsmith Award, and co-founded the NHSBT Clinical Studies Unit, its Systematic Reviews Initiative for transfusion medicine and the Transfusion Evidence Library. He is a former Chair of the international research group, the BEST Collaborative, and is the President of AABB (2018-2019). He has received numerous research grants and is the author of more than 250 articles.

Alexander Vlaar, intensivist and principal investigator, received his PhD from the University of Amsterdam (UvA) in 2010 for his research into transfusion-related acute lung injury (TRALI), a potentially fatal side effect of blood transfusions. As principal investigator at the Amsterdam University Medical Centra (UMCA) and the UvA he focuses his research on infusion related morbidity and mortality in the critically ill. His is the current chair of the Transfusion Task Force of the European Society of Intensive Care Medicine (ESICM). He has received numerous research grants and several national and international awards for his research.