This bar graph identifies the total number of suspected reactive donations and presumed viremic donations (PVDs) by week of donation as identified through NAT. A PVD is defined as 1) a WNV-initially reactive donation with a signal-to-cutoff (S/CO) ratio of greater than or equal to 17 using the WNV Transcription-mediated Amplification Assay (Hologic/Gen-Probe and Novartis) or 2) a WNV-initially reactive donation with an S/CO ratio of less than 17 if upon repeat testing the sample is repeatedly reactive. Similarly, WNV-initially reactive donations identified using the Cobas TaqScreen WNV Test (Roche) should be retested to determine if they are PVDs based on repeat reactivity. Suspected reactive donations are reported by facilities as they occur based on the test results.
This electronic data network, initiated in 2006, was developed by the WNV Task Force. The task force includes representatives from AABB, the Centers for Disease Control and Prevention (CDC), U.S. Department of Health and Human Services, the Food and Drug Administration (FDA), U.S. Department of Defense, American Red Cross, America’s Blood Centers, Canadian Blood Services and United Blood Services. The WNV Task Force accepted this charge as part of AABB’s mission to improve patient safety with respect to transfusion medicine and, in particular, to fulfill its stated goal of taking a leadership role in creating a biovigilance system in the United States.
This tool is intended to support and enhance an identification and tracking initiative that AABB had developed in partnership with FDA and CDC when WNV first became a public health concern. This resource is not intended to supplant or replace public health agency data collection, or to predict the occurrence, frequency or location of WNV, but rather to support public health agencies, blood collection facilities and transfusion services.
The data posted on this Web site are provided by third parties and are not verified by AABB. Accordingly, AABB makes no guarantee or promise that the data are current, valid, or accurate. No content on this site is intended to constitute professional advice, whether medical, legal or otherwise. AABB expressly disclaims any liability or loss that may arise either directly or indirectly from relying on the information, services or other material on this site.
Reporting facilities that are HIPAA-compliant should report only patient data that has been de-identified in accordance with HIPAA de-identification standards, according to which only states of residence, not zip codes, may be reported. AABB is not responsible for reporting facilities’ compliance with federal, state or local laws or regulations.
WNV Blood Donor Data Collection and Reports
WNV Blood Donor Data Collection (password-protected)
WNV Blood Donor Data Reports (password-protected)
WNV Biovigilance Network Training Guide (PDF)
WNV Biovigilance Network FAQ
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