BUNDLE: AABB Guide to Prenatal and Postnatal Immunohematology Testing and Pediatric Transfusion: A Handbook, 5th edition - Print

Product Code: 233080

This bundle brings together two great pediatric resources.

In the era before neonatal exchange transfusion, intrauterine transfusion, amniocentesis, ultrasonography, and Rh immunoglobulin (RhIG) prophylaxis, Rh(D) hemolytic disease of the fetus and newborn (HDFN) was a major cause of perinatal death. Thanks to these and other key advances the morbidity and mortality associated with Rh(D) HDFN have declined markedly.

However, some advances have come with new concerns. For instance, multi-hospital healthcare systems have increased in size and number and hospitals, practitioners, and laboratories have become more specialized. Thus, the caregiver who orders prenatal and perinatal testing may not practice in the same facility where testing is performed. RhIG may not be dispensed by the transfusion service and may fall under the purview of the pharmacy. In this landscape, the management of prenatal and perinatal patients, especially those with a history of sensitization, requires close communication, collaboration, and coordination between clinicians, pharmacists, and transfusion service personnel.

The intent of this AABB Guide to Prenatal and Postnatal Immunohematology Testing is to assist in promoting a common understanding among those professionals formulating prenatal and perinatal testing practices and to discourage the use of outdated, non-evidence-based practices and protocols. After laying a solid foundation on the fourfold objectives of prenatal and perinatal testing the Guide provides a thorough exploration of the following key topics:

Routine testing during pregnancy, including purpose and timing.
Management of the alloimmunized patient, including those with different, non-Rh(D), alloantibodies that can cause HDFN.
Testing at delivery for both mother and neonate/cord blood.
The use of RhIG prophylaxis, including timing and dose.

Where possible, the content is succinctly presented in tabular format. In circumstances where controversies exist or the data are limited or inconsistent, the Guide highlights both pros and cons, encouraging practitioners to keep abreast of future discoveries.

Written by Lani Lieberman, MD, FRCP(C); Gwen Clarke, MD, FRCP(C); Mark Fung, MD, PhD; Wen Lu, MD; Theresa A. Nester, MD for the Transfusion Medicine Section Coordinating Committee

Pediatric Transfusion: A Handbook, 5th edition is a concise yet comprehensive reference book for all practitioners who transfuse neonatal and pediatric populations. This book is invaluable for physicians treating patients in the hospital or those answering questions while on call in the blood bank. Written in response to questions from a variety of professionals in the field, this unique book presents, in one easy-to-use handbook, information that typically would require multiple volumes of text. Charts and tables outline information concerning volumes of blood components and doses of medication for neonatal and pediatric patients. Contributors with a wealth of practical experience share their knowledge in a resource that fits conveniently in your lab coat pocket.

This edition includes the latest updates addressing patients with special transfusion needs, including neonates, patients undergoing extracorporeal membrane oxygenation, cardiovascular surgery patients, trauma patients, sickle cell disease patients, and other pediatric patients who require chronic transfusion support. In addition, the latest updates on pathogen inactivation and the use of new blood products in children are discussed.

Recent years have seen tremendous strides in the use of recombinant and nonrecombinant products. For pediatric patients with specific coagulation deficiencies, such as hemophilia A and B, the use of extended half-life products, as well as products (non-factor-derived) that mimic the actions of coagulation factors, are now available for use. With these developments in mind, this edition has an extensively updated coagulation section, so the reader can become familiar with “new biologics” as preferred alternatives to traditionally used blood products.

In addition, “ABC-PICU,” which examined the age of red cells on outcomes in critically ill children, is discussed in this edition. The latest information on the use of pathogen-inactivated blood products is also included.

Edited by Edward C.C. Wong, MD; Susan D. Roseff, MD; and Nick Bandarenko, MD

PRINT EDITION: AABB, 2023, softcover, 56 pages, ISBN: 978-1-56395-420-7, and 2020, AABB, softcover, 299 pages, 978-1-56395-405-4

Product code: 233080
Member price: $76
Nonmember price: $104