Scientific Research Grant Scholar Recipients

Annamaria Aprile, MD, PhD
Ospedale San Raffaele
Project: Exploring the role of FGF23 in β-thalassemia: a novel target to ameliorate bone marrow microenvironment and anemia
Project Led To: Discovery of an underexplored role of FGF23 in bone and BM niche defects in a primary anemia, as a condition of chronic EPO stimulation.

Agnieszka Czechowicz, MD, PhD
Stanford University
Project: Determine genetic factors and mutations that regulate progression to bone marrow failure and myeloid neoplasia in Fanconi anemia
Project Led To: This powerful foundation positions our group to better understand Fanconi anemia and others like it - with the aspiration to elucidate important underlying biology that is critical to the maintenance of the blood and immune system.

Delfim Duarte, MD, PhD
Instituto de Biologia Molecular e Celular (IBMC)
Project: Targeting the bone marrow vascular microenvironment to improve hematopoietic stem cell therapies in acute myeloid leukemia
Project Led To: An observance that AML cells produce CXCL2 in response to TNF and that CXCL2 itself affects the survival of CXCR2-expressing blood vessels. We are currently evaluating HSCT outcomes after inhibition of the CXCL2-CXCR2 axis in AML.

Pietro Genovese, BSc, MSc, PhD
Dana-Farber Cancer Institute
Project: Engineering immunotherapy resistant hematopoiesis to treat high-risk acute myeloid leukemia
Project Led To: Successfully modifying normal bone marrow stem cells used for allogeneic transplantation in order to make them resistant to targeted therapies such as CAR-T cells. In preclinical studies, this strategy allowed the administration of highly effective immuneotherapies targeting a protein essential for tumor survival without the risk of severe toxicity on the healthy tissue counterpart.

Saba Ghassemi, PhD
University of Pennsylvania
Project: Redirecting quiescent T cells with chimeric antigen receptors (CARs) for adoptive immunotherapy
Project Led To: Research examining a minimized process to generate highly functional CAR T cells within a day, which can reduce costs, conserve limited resources, and has the potential to decentralize CAR T-cell manufacturing to local hospital laboratories, reducing many logistical challenges.

Areum Han, PhD
Boston Children’s Hospital
Project: The role of the RNA editor-exonuclease axis in RNA turnover during erythropoiesis: from mouse embryo studies to in vitro modeling
Project Led To: An investigation into which genes are regulating the role of the RNA editor-exonuclease axis in RNA turnover during erythropoiesis. We tracked back the role of RNA regulators during blood development and discovered that the RNA editor and downstream exonuclease govern this maturation. Encouraged by the finding, we are progressing to humanized mice and human stem cell studies to advance this discovery for patients.

Marie Hollenhorst, MD, PhD
Stanford University
Project: CMP-Neu5Ac: A Central Molecule in Bleeding Diseases and Mediator of a Novel Platelet Effector Function
Project Led To: We now have a precise map of the position of sialic acid-containing glycans on what has been described as the dominant platelet surface sialoglycoprotein. This provides an unprecedented level of biochemical detail regarding sialic acid on the platelet surface and provides a foundation on which further studies regarding the biology of platelet clearance driven by desialylation can be built.

Robert H. Lee, PhD
University of North Carolina
Project: Efficacy of platelet transfusion in the setting of anti-platelet therapy
Project Led To: Findings that suggest that in patients with TP, the use of single APT (aspirin or P2Y12 inhibitor) could be used to maintain protection from thrombosis without a substantial risk of major bleeding and that hemostasis may only require a subpopulation of uninhibited platelets.

Larry Luchsinger, PhD
New York Blood Center
Project: Caveolae Coordination of Signal Transduction Pathways in Hematopoietic Stem Cell Function
Project Led To: Findings that HSCs have elevated expression of certain genes involved in plasma membrane organization that may control stem cell properties. Our first Aim is to characterize the expression of these genes between HSCs and differentiated cells and to determine the functional consequence to HSCs when we either delete or over-express these genes. The second Aim is to determine the molecular pathways that are influenced by caveolae with the goal of uncovering new mechanisms that could be leveraged to improve HSC transplantation or ex vivo blood production.

Evan Orenstein, MD
Emory University
Project: Improving Patient Blood Management in Pediatrics through Automated Medical Error Detection and Clinical Decision Support Design
Project Led To: This work has led directly to a 23% reduction in ordering errors for irradiated products, an 18% reduction in transfusions administered faster than the recommended rate, and a 76% reduction in inappropriate special processing orders for sickle cell disease patients.

David Roh, MD
Columbia University
Project: Red Blood Cell Contribution to Coagulopathy and Cerebral Oxygenation after Intracerebral Hemorrhage
Project Led To: With the collective advances during my AABB Foundation funding period, I was able to establish the ground-level infrastructure needed to begin my transition into an independent clinical investigator at the intersection of stroke and transfusion medicine. Our group has now developed techniques to be able to assess clinical hemostatic efficacy and cerebral oxygenation changes in response to specific transfusion based, and transfusion sparing approaches in intracerebral hemorrhage patients. The work that I have accomplished through the AABB Foundation’s support will reinforce future efforts and focus needed at the intersection of stroke and transfusion medicine. Our initial findings have demonstrated that there are relevant laboratory and transfusion-based approaches (including vein to vein, donor to recipient characteristics) that have impacts on clinical outcomes in stroke patients, and specifically those with intracerebral hemorrhage. Our group’s next steps will be to rigorously investigate alternative and novel transfusion-based approaches, accounting for transfusion specific (including donor to recipient) characteristics for these patients in efforts to develop novel therapeutic approaches to improve their long-term outcomes.

Benjamin Samelson-Jones, MD, PhD
Children's Hospital of Philadelphia
Novel Therapeutics for Hemophilia B: A Rational Pursuit of Bioengineered Factor IX Variants with Enhanced Clotting Activity

Vijay Bhoj, MD, PhD
University of Pennsylvania
Dissecting the Humoral Response to FVIII for Therapeutic Applications

Robert Nickel, MD, MSc
Children's Research Institute
Hydroxyurea and Transfusion (HAT): Pilot Study of Combination Therapy for Patients with Sickle Cell Anemia

Francesca Vinchi, PhD
New York Blood Center
Role of heme-activated macrophages in Acute Chest Syndrome

Arunoday K. Bhan, PhD
Boston Children's Hospital
“Identifying megakaryocyte maturation pathways critical for platelet generation.”

Avital Mendelson, PhD
Lindsley F. Kimball Research Institute
New York Blood Center
“A biomimetic niche for platelet formation in vitro.”

Antonella Nai, BSc, MSc, PhD
Ospedale San Raffaele, Italy
“Targeting the second transferrin receptor for amelioration of severe malarial anemia.”

Hideyuki Oguro, PhD, MSc, BSc
The Jackson Laboratory
“Induction of hematopoietic stem cell proliferation and mobilization by estrogen receptor signaling.”

Moritz Stolla, MD, PhD
Bloodworks Northwest Research Institute
“Cold-stored Platelets for the Reversal of Dual Antiplatelet Therapy.”

Lindsey A. George, MD
University of Pennsylvania, Perelman School of Medicine
“Prothrombin activation in vivo: contribution of membrane binding for effective hemostasis and development of a novel warfarin reversal strategy.”

David Gibb, MD, PhD
Yale University School of Medicine
“Characterizing innate immune mechanisms underlying the link between inflammation and RBC alloimmunization”

Troy Lund, MD, PhD
Regents of the University of Minnesota
“Adipokine Regulation of Hematopoietic Cell Homing”

Sandhya Panch, MBBS, PPH
National Institutes of Health
“Barcoded macaque transplants: A novel approach to study Human Umbilical Vein Endothelial Cell (HUVEC) expanded hematopoietic stem and progenitor cell (HSPC) engraftment and repopulation kinetics”

Juliana Xavier-Ferrucio, PhD
Yale University
“Megakaryocyte erythroid progenitor fate specification under iron and oxygen deficiency”

Mobin Karimi, MD, PhD
University of Pennsylvania
“Separation of GVHD from GVT responses by modulation of T cell signaling pathways”

James Ankrum, PhD
The University of Iowa
“Elucidating the role of FOXO3 in restoring the potency of in vitro expanded mesenchymal stem cells.”

Yacine Boulaftali, PhD
Inserm U1148- Laboratory for Vascular Translational Science (LVTS), France
“Neutralizing serpinE2 : a new medical concept of treating haemophilia.”

Angelo D’Alessandro, PhD
University of Colorado Denver – Anschutz Medical Campus
“The role of adenosine signaling in the preservation of energy metabolism of stored erythrocytes”

Neil Hanchard, MD, PhD
Baylor College of Medicine
“A genomics approach to transfusion responders in sickle cell disease”

Sarika Saraswati, PhD
Vanderbilt University
“New Strategies to Augment Efficacy of Stem Cell Therapy for Therapeutic Revascularization”

Richard Francis, MD, PhD
Columbia University Medical Center
“Effect of glucose-6-phosphate dehydrogenase deficiency on red blood cell storage”

Krystalyn Hudson, PhD
Bloodworks Northwest Research Institute
“Establishment and maintenance of lymphocyte tolerance to red blood cell antigens”

Ramesh Nayak, PhD
Hoxworth Blood Center, University of Cincinnati
“Angiotensin in stem cell recruitment and mobilization”

Julie Peterson, PhD
Blood Research Institute, BloodCenter of Wisconsin
“Recombinant glycoprotein fragments for improved detection of alloantibodies in Neonatal Alloimmune Thrombocytopenia (NAIT)”

William Savage, MD, PhD
Brigham and Women’s Hospital
“Aeroallergen-specific antibodies in allergic transfusion reactions.”

Claude Tayou Tagny, MD, MS, MSc
University of Yaoundé, Cameroon
“Risk Factors of HIV infection in Sub-Saharan Africa blood donor – A pilot phase in Cameroon”

George J. Murphy, PhD
Center for Regenerative Medicine (CReM)
“Pluripotent stem cells in the modeling of blood disease and the development of potentially transfusable human red blood cells and platelets”

Michael Nemeth, PhD
Roswell Park Cancer Institute
“Improving Bone Marrow Transplantation Through Targeting Hematopoietic Stem Cell Quiescence”

Robert B. Neuman, MD
Emory University, School of Medicine
“Physiologic effects of RBC storage in chronic transfusion recipients: vasoreactivity, exercise capacity, and oxygen consumption”

Anand Padmanabhan, MD, PhD
BloodCenter of Wisconsin
“Role of IgA and IgM Immunoglobulins in Heparin-Induced Thrombocytopenia and Thrombosis (HIT)”

Tracey L. Papenfuss, DVM, MS, PhD
The Ohio State University, Waxner Medical Center, Regenerative Medicine
“Development of myeloid derived suppressor cell therapy for the treatment of inflammatory disease”

Sean Stowell, MD, PhD
Emory University, School of Medicine
“Characterization of Immunity and Tolerance Following RBC Transfusion”

Stella T. Chou, MD
University of Pennsylvania, Perelman School of Medicine
“Red blood cell generation from human induced pluripotent stem cells: a new tool for transfusion medicine”

Stephanie Eisenbarth, MD, PhD
Yale University
“Identifying Innate Immune System Pathways Critical for RBC Alloimmunization”

William Janssen, MD
National Jewish Health, University of Colorado, Denver
“Degradation of the Pulmonary Endothelial Glycocalyx in Transfusion Related Acute Lung Injury (TRALI)”

Nilam Mangalmurti, MD
University of Pennsylvania
“Role of Red Cell Advanced Glycation End products in Endothelial Dysfunction”

Henrique Viega-Fernandes, DVM, PhD
Instituto de Medicina Molecular (IMM), Portugul
“Modulation of RET Signaling in Hematopoietic Stem Cell Transplantation”

Jianhua Yu, PhD
The Ohio State University
“Preclinical Studies of the Combination of Recombinant Human FLT3 Ligand and AMD3100 to Mobilize Allogeneic Blood Cell Grafts for Transplantation”

Julie Audet, PhD
University of Toronto, Canada
“Directed Expansion and Differentiation of Blood Progenitor Cells using TAT-Conjugated Transcription Factors”

Attilio Bondanza, MD, PhD
H San Raffaele, Italy
“Cell Therapy of Multiple Myeloma by Genetic Redirection of T Cells Against CD44v6”

Mettine H.A. Bos, PhD
Leiden University Medical, Netherlands
“Mechanisms Regulating the Macromolecular Enzyme Complex Assembly in Blood Coagulation”

Swapan Kumar Dasgupta, PhD
Baylor College of Medicine
“Signaling Cascade Leading to Phosphatidylserine Exposure in Stored Platelets”

Eldad Hod, MD
Columbia University Medical Center
“Effect of Repeat Blood Donation on Atherosclerosis and Cancer Risk in Murine Models”

Katherine MacNamara, PhD
Albany Medical College
“IFNγ-Mediated Control of Hematopoietic Stem and Progenitor Cell Differentiation”

Nicolas Pineault, PhD
Héma-Québec, Canada
“A cellular-based therapy to prevent or reduce thrombocytopenia.”

Rahima Zennadi, PhD
Duke University Medical Center
“Regulation by nitric oxide of sickle red cell adhesion.”

Rachel Bercovitz, MD
The University of Colorado Denver,
“Transfusion-related Acute Lung Injury (TRALI) from Plasma Products: Understanding the Pathogenesis of Immune- and Non-Immune-Mediated TRALI and Determining Methods to Mitigate TRALI Risk”

Alicia Barcena, PhD
University of California, San Francisco
“Evaluation of human fetal membranes as a source of hematopoietic stem cells.”

Jonathan Finn, PhD
Children's Hospital of Philadelphia
“The Development and Safety Characterization of Novel Hyper-functional Factor IX Variants for the Treatment of Hemophilia B”

Daniel Gonzalez-Nieto, PhD
Cincinnati Children's Hospital Medical Center
“Connexin-43 in the hematopoietic stem cell niche.”

Taku Kambayashi, MD, PhD
University of Pennsylvania
“The role of GMCSF in regulatory T-cell proliferation and homeostasis.”

Rose Beck, MD, PhD
Case Western Reserve University, School of Medicine
“Notch-induced NK Cells for Cell Therapy in Hematologic Maligancy”

Chance John Luckey, MD, PhD
Brigham and Women's Hospital Blood Bank
“Directed differentiation of embryonic stem cells by regulated caspase9 cleavage of zona-occludens2.”

Beth Shaz, MD
Emory University School of Medicine
“Blood Donation considerations in African Americans”

Christine M. Cserti-Gazdewich, MD, FRCP
University of Toronto, Canada
“Cytoadherence in Pediatric Malaria (CPM) Study.”

Cheryl Ann Lobo, PhD
New York Blood Center
“Role of Red Cell Glycophorins in the Invasion of Babesia divergens”

A. Louise McCormick, PhD
Emory University, School of Medicine
“The role of cytomegalovirus-encoded inhibitor of caspase-8 activation, vICA, in disease following transfusion or transplantation”

Saul Yedgar, PhD
Hebrew University of Jerusalem, Israel
“Repair of red blood cell flow properties for transfusion therapy: the effect fo leukoreduction and rejuvenation”

Peiman Hematti, MD
University of Wisconsin-Madison
“ESC-derived MSC transplantation in NOD/SCID mice”

Jeanne E. Hendrickson, MD
Emory University, School of Medicine
“Effect Of Host Inflammation On Alloimmunization To RBC Transfusion”

Marcus O. Muench, PhD
Blood Systems Research Institute
“In Utero Transplantation of The Hematopoietic Microenvironment”

Lirong Qu, MD, PhD
University of Pittsburgh
“Detection and Quantification of Human Herpesvirus 8 (HHV-8) Genomes in US Blood Donors with Sensitive real-time PCR”

Jill Storry, PhD
Lund University, Sweden
“Characterization of the Vel Blood Group System”

Astrid Van Halteren, MD, PhD
Leiden University Medical Center, Netherlands
“Pregnancy-Induced Minor Histocompatibility Alloimmune T Cells and Fetal Microchimerism: Friends of Foes?”

Lan Zhou, PhD
Case Western Reserve University
“Regulation of Granulopoiesis by Fucosylated Glycans Through Selectin-Mediated Adhesion and Fringe-Modified Notch Signaling Pathways”

Marie Bleakley, MD
Fred Hutchinson Cancer Research Center
“Discovery of Antigens for Targeted Therapy of Leukemia”

Brian S. Custer, MPH, PhD
Blood Systems Research Institute
“Retrospective Cohort Analysis of Return Behavior in Temporarily Deferred and Eligible Voluntary Blood Donors”

Lana Kaiser MD, DVM
Michigan State University
“Transfusion Iron Overload And Cardiac Arrhythmias”

Jose Cancelas, MD, PhD
Cincinnati Children's Hospital Medical Center
“Mobilization of Hematopoietic Stem Cells by Reversible Inhibition of Rac-Type Rho GTPases: Demonstration of Proof-of-Concept for Future Clinical Applications”

Allison Hubel, MS, PhD
University of Minnesota
“Post Thaw Processing of Hematopoietic Stem Cell Products”

Nora Ratcliffe, MD
VAMC White River Junction and Manchester
“The Role of Dendritic Cell Subsets in Autoimmune Myocarditis and the Potential for Cytotherapy”

James C. Zimring, MD, PhD
Emory University, School of Medicine
“Selective Induction of Allotolerance in Bone Marrow Transplantation”

Ognjen Gajic, MD
Mayo Clinic College of Medicine
“Transfusion-Related Acute Lung Injury in the Medical Intensive Care Unit”

Andres Hidalgo, PhD
Mount Sinai School of Medicine
“Optimizing Cord Blood Transplantation by Upregulation of Selectin Ligands”

Qizhen Shi, MD, PhD
Medical College of Wisconsin
“Targeting Human Platelet Glycoprotein Ibα Gene Expression to the Platelets of Bernard-Soulier Syndrome Mice”

X. Long Zheng, MD, PhD
Children's Hospital of Philadelphia
“Characterization of Autoantibodies Directed Against ADAMTS13 Metalloprotease Underlying Thrombotic Thrombocytopenic Purpura”

Yvonne H. Datta, MD
Medical College of Wisconsin
“Genetic Mapping and Characterization of the Bleeding Disorder in the Fawn-Hooded Hypertensive Rat”

Carl S. Goodyear, PhD
University of California, San Diego
“Mechanisms of Immunomodulation by Protein A Pheresis”

Suresh Shelat, MD, PhD
University of Pennsylvania
“Characterization of the Human Immune Response in Heparin-Induced Thrombocytopenia Using Repetoire Cloning”

Steven L. Spitalnik, MD
Columbia University
“Hemolytic Transfusion Reactions: A Transgenic Mouse Model”

Larry J. Dumont, MBA
Gambro BCT
“Human Cytomegalovirus (HCMV) Reactivation – Human Exposure Model and Mechanism D”

Sandra L. Haberichter, PhD
Blood Research Institute; Blood Center of SE Wisconsin
“The Role of the von Willebrand Factor Propeptide in Targeting vWF to the Regulated Storage Pathway”

Michael Hodsdon, MD, PhD
Yale University
“Regulation of von Willebrand Factor Susceptibility to Proteolytic Cleavage by a Plasma Metalloproteinase”

Peter L. Perrotta, MD
SUNY @ Stony Brook
“Role Of Apoptotic Mechanisms In Platelet Dysfunction And Death”

Maria Bettinotti, PhD
National Institutes of Health
“Molecular Basis of Polymorphisms in Neturophil Antigen NB1: CD177”

Walter L. Biffl, MD
Denver Health Medical Center
“Blood Transfusion-Provoked Delay in Neutrophil Apoptosis in Trauma may be Altered by Modifying Transfusion Practices”

James D. Gorham, MD, PhD
Dartmouth Medical School
“T Cell Cytokine Secretion in a Murine Model of Transfusion-associated ImmunoModulation (TRIM)”

Patricia Kopko, MD
Sacramento Medical Foundation Blood Centers
“The Association of HLA Class II Antibodies and White Blood Cell Activation with Transfusion-Related Acute Lung Injury”

Jonathan David Kurtis, MD, PhD
Brown University
“Novel Erythrocyte Invasion Protiens As Vaccines For Human Falciparum Malaria”

Krista V. Lankford, MD
Emory University
“Mechanisms of Action of Therapeutic Plasma Exchange (TPE) in Thrombotic Metalloprotease (MP) and Its Antibody Inhibitor (IMP)”

Karina Yazdanbakhsh, PhD
New York Blood Center
“Recombinant Antigens as Tools for Identification of Alloantibodies in Patients' Sera”

Jeffrey L. Carson, MD
UMDNJ-Robert Wood Johnson Medical School
“The Effect of Anemia and Transfusion on Postoperative Delirium”

David G. Meyers, MD
Kansas University Medical Center
“A Historical Cohort Study of the Effect of Lowering Body Iron Through Blood Donation on Cardiac Events”

Andrey Skripchenko, PhD
Holland Laboratory, American Red Cross
“The Mechanism(s) of virus Photoinactivation by Dimethylmethlene Blue”

Robertson Davenport, MD
University of Michigan Department of Pathology
“A Murine Model of Acute Hemolytic Transfusion Reactions”

Peter Larson, MD
University of North Carolina, Chapel Hill
“The Role of the GIA Domain in the Function of Vitamin K-dependent Coagulant Proteins”

Jo Anna Reems, PhD
Blood Systems Foundation
“Ex Vivo Expansion of Human Umbilical Cord Blood Hematopoietic Progenitor Cells: Evaluation of their Function in a Mouse Transplant Model”

Douglas P. Blackall, MD
University of California, Los Angeles
“Recombinant Blood Group Antigen Engineering: Glycophorin A as a Model Glycoprotein”

Scott Burger, MD
University of Minnesota, Minneapolis
"Adhesive Interactions in Hematopoietic Cell Homing"

Raymond L. Comenzo, MD
Boston Medical Center
“Immunoglobulin Genes and DNA Vaccines: Synergy With Stem-Cell Transplant?”

Timothy C. Fisher, MB, Ch.B
USC School of Medicine
“Red Blood Cell Antigen Masking by Covalently-Bound Polyethylene Glycol”

Petr Jarolim, MD
Brigham and Women's Hospital
"Characterization of Blood Group Antigens Carried by Erythroid Band 3"

Diane Krause, MD, PhD
Yale University, School of Medicine
"Regulation of Cd34 Expression During Hematopoiesis"

Eleanor Pollack, MD
The Children's Hospital of Philadelphia
“Substrate and Inhibitor Binding Sites of Human Coagulation Factor Xa”

John Donald Roback, MD, PhD
Emory University
“The Role of Leukocytes in Transfusion-Transmitted Cytomegalovirus (TT-CMV) Infection: Development of an Animal Model”

John Rosenberg, PhD
Blood Center of Southeast Wisconsin
“Impact of von Willebrand Factor on Factor VIII Gene Targeting”

Louis V. Kirchhoff, MD
University of Iowa
"Use of Recombinant Trypanosoma Cruzi Proteins for Serologic Diagnosis of Chagas Disease"

Dorothea Zucker-Franklin, MD
New York University Medical Center
"Studies on Prevalence and Transmissibility of HTLV-I/II Tax"

Emily Baron-Casella, PhD
The Johns Hopkins University, School of Medicine
"Identification of the Epitopes and Antibodies Involved in the HPA-3 (Bak) and HPA-4 (Pen) Alloantigen Systems"

Tylis Y. Chang, MD
University of Pennsylvania
"ABO Antibodies: The Ontogeny of the "Natural Repertoire"

Laura Cooling, MD
University of Iowa
"Population Differences in Blood Group Antigen Expression Among Normal Platelet Donors"

Brian Curtis, BS, MT(ASCP)SBB
The Blood Center of Southeastern Wisconsin
"Role of ABO Blood Group Incompatibility in the Pathogenesis of Neonatal Alloimmune Thrombocytopenic Purpura"

Louis A. DePalma, MD
The George Washington University Medical Center
"Gene Expression in Activated Cord Lymphocytes: Relevance to Neonatal Immunohematology"

Loren D. Fast, PhD
Rhode Island Hospital
"The Immunological Consequences of Blood Transfusion: Early Events"

Martha Osborne
Central Kentucky Blood Center
"Retaining First Time Donors: Testing the Effectiveness of Interventions Designed to Increase Personal Perception as a Committed Donor"

Robert I. Roth, MD, PhD
Department of Veterans Affairs Medical Center
"A Mechanism for Endothelial Cell-mediated Thrombosis: Deleterious Consequences of the Interaction of Cell-free Hemoglobin and Bacterial Endotoxin"

Gerald Soslau, PhD
Hahnemann University
"Response of Stored Platelets to Paired Agonists in the Presence and Absence of Extracellular ATP"

Connie Westhoff, PhD
University of Nebraska, Lincoln
"Targeted Deletion of the Rh Genes in Human Erythroleukemia Cells"

Neil Young, Msc, FIBMS
University of Oxford, England
"Molecular Analysis of Alloreactivity in Recipients of HLA-One-Haplotype-Matched or Fully HLA-Mismatched Pre-Transplant Blood Transfusions"

Francesco Bertolini, MD, PhD
Maugeri Foundation, Pavia Medical Center, Italy
"Collection and Ex-Vivo Expansion of Placental Blood-Derived Hematopoietic Progenitors for Transplantation"

Douglas P. Blackall, MD
University of Tennessee
"Human Blood Group Glycophorins as Receptors for the Plasmodium falciparum Malaria Parasite"

Walter H. Dzik, MD
New England Deaconess Hospital
"Transient Microchimerism Following Allogeneic Blood Transfusion"

Susan H. Eshleman, MD, PhD
Case Western Reserve University
"Regulation of Protein Glycosylation: Characterization of Glycosylation Signals for Recombinant Protein Design"

Maryanne Keashen-Schnell
American Red Cross Blood Services
"Antibody Detection in the Thrombocytopenic Disorders of Pregnancy"

Alan H. Lazarus, PhD
St. Michael's Hospital, Canada
"Study of a B-cell Regulatory Pathway to Delay or Prevent Platelet Alloimmunization in a Human-PBMC-SCID Mouse Model"

Malcolm R. MacKenzie, MD
Sacramento Medical Foundation Center for Blood Research

Theodore Wun, MD
University of California Davis Cancer Center
"Thrombopoietin Effects on Human Platelets"

Paul F. Bray, MD
The Johns Hopkins University, School of Medicine
"Application of Novel Molecular Methods to Genotype and Identify New Platelet Specific Antigens"

Umakant J. Dumaswala, PhD
Hoxworth Blood Center
"Glutamine Improves Red Cell Preservation"

Cheng-Han Huang, MD, PhD
New York Blood Center
"Studies on Human S-s-U and S-s-U+ Red Blood Cells–Molecular Basis, Phenotypic Heterogeneity and Relationship to Other Surface Markers of Glycophorin"

Christine S. Rinder, MD
Yale University School of Medicine
"An In Vitro Model of the Effects of Platelet Transfusion on Leukocyte Function"

S.M. Hossein Sadrzadeh, PhD
New England Deaconess Hospital
"Oxygen Free Radical Damage of Gamma-Irradiated Blood"

Jeffrey L. Carson, MD
UMDNJ - R.W. Johnson Medical School
"Cost Effectiveness of Autologous Blood Transfusion"

Ellen P. Klohe, PhD
Inland Northwest Blood Center
Spokane, Washington
"Effects of Methyldopa on Leukocyte Subpopulations"

Marion Reid, PhD
New York Blood Center
"Studies on the Surface Markets of Glycophorin in Molecules in Human Red Blood Cells"

Rosetta Sue Shirey, MS, MT(ASCP)SBB
The Johns Hopkins Hospital
"An Animal Model of DSTR and DHTR"

Michael P. Busch, MD, PhD
Irwin Memorial Blood Centers
"Impact of Homologous Blood Transfusion on HIV Replication and Disease in Vivo"

Loren D. Fast, PhD
Rhode Island Hospital
"Blood Transfusion and GVHD: Induction, Prevention and Modulation"

Linda L. Kelley, PhD
Vanderbilt University
"Erythropoietin Regulation of the Cell Cycle in Erythroid Progenitor Cells"

Joann Moulds, PhD
University of Texas Medical School
"Determination and Localization of Human Blood Group Polymorphisms on Complement Receptor One (CR1)"

Raymond L. Comenzo, MD
Boston Medical Center
"On the Role of Fibronection in Peripheral Blood Progenitor Cell Amplification"

Christopher D. Hillyer, MD
Emory University Hospital Blood Bank
"Peripheral Blood Stem Cells for Allogeneic Transplantation: Development of an Animal Model-Initial Phase Investigations"

Hwai-Tai C. Lam, MS, MT(ASCP)SBB
University of California, Los Angeles
"A Cost-Effective Study of a Prospective Utilization Monitoring Program for Transfusion Practice"

Peter J. Larson, MD
University of North Carolina, Chapel Hill
"The Role of the GIA Domain in the Function of Vitamin K-dependent Coagulant Proteins"

Donald L. Siegel, PhD, MD
Hospital of the University of Pennsylvania
"Biology of Human Warm Autoimmune Hemolytic Anemia"

Priscilla Y.L. Yam, MS, FIMLS
University of California, Los Angeles
"The Detection of Minimal Residual Disease Using T-Cell Receptor Gene Rearrangements and the Polymerase Chain Reaction"

Douglas M. Lublin, MD, PhD
Washington University
"Molecular Biological Approaches to Immunohematology: Pilot Study of Cromer Blood Group"

Allen Mayer, MD, PhD
Irwin Memorial Blood Center
"Adaptation of Capillary Separation to PCR Amplification for Donor Infectious Disease Screening"

C. Ann Rearden, MD
University of California, San Diego
"Antigenicity and Autogenicity of the MN Blood Group Sialoglycoprotein Glycophorin A"

Brian R. Smith, MD
Yale University, School of Medicine
"Platelet-Leukocyte Interactions"

Douglas M. Smith, MD
University of Nebraska Medical Center
"Allogeneic Peripheral Blood Stem Cell Transplantation in Yucatan Miniature Swine"

Neil Blumberg, MD
University of Rochester Medical Center
"Comparison of the Clinical and Immunologic Effects of Autologous or Homologous Blood Transfusions in Patients Undergoing Spinal Fusion Surgery"

Janice P. Dutcher, MD
Montefiore Medical Center
"Evaluation of Hematologic Changes Associated with Interlukin-2 Administration to Patients with Metastatic Malignancy and Evaluation of Migration of Activated Autologous Lymphocytes in these Patients"

Walter H. Dzik, MD
New England Deaconess Hospital
"Leukopoor Platelet Concentrates: Development and Evaluation of a Method for Preparing Leukocyte Depleted Platelet Concentrates from Single Units of Whole Blood"

Sandra J. Nance, MS, MT(ASCP)SBB
American Red Cross, Los Angeles-Orange Counties Region
"A Comparison of the Efficiency of the Monocyte Monolayer Assay IgG Subclassing, OD450 Amniotic Fluid, and Ultrasonography in Prediction of the Severity of Hemolytic Disease of the New Born"

James A. Sloand, MD
Highland Hospital
"Characterization of Platelet Glycoprotein Ib in Chronic Renal Failure"

Timothy H. Carlson, PhD
University of New Mexico, Albuquerque
"Preparation and Properties of an Improved Antithrombin III Concentrate"

Thomas S. Kickler, MD
The Johns Hopkins Hospital
"Antiallotypic Antibodies in Platelet Transfusion Recipients–Their Clinical Significance"

Joann Moulds, MS, MT(ASCP)SBB
University of Texas, Houston
"Quantitation of C4A (Rodgers) and C4B (Chido) in Order to Study Their Role in Complement Mediated Pathology"

Harry E. Prince, PhD
American Red Cross, Los Angeles-Orange Counties Region
"Lymphocyte Activation by Oxidized Erythrocytes: Characterization of the Responding Cells and the Cellular Interactions Required"

Chester Andrzejewski, PhD, MD
University Intramural Correspondence
"New Assessments of Anti-Erythrocyte Autoantibody Heterogeneity in Immune Hemolytic States"

John B. Lowe, MD
Howard Hughes Medical Institute
"The Molecular Biology of the Human A Blood Group Glycosyltransferases"

Paul Mintz, MD
University of Virginia Medical Center
"Correlation of Non-invasive Assessment of Platelet Morphology with Platelet Recovery and Survival"

David Scrivner, MD
American Red Cross, St. Louis Bi-State Chapter
"Hydrocortisone Impairs Lak Activity by Inhibition of Effector/Target Cell Binding"

Edward L. Snyder, MD
Yale University, School of Medicine
"Calcium-Dependent Proeolysis of Actin During Storage of Platelet Concentrates"

Edward J. Victoria, PhD
University of California, San Diego
"Transmembrane Skeletal Association of the RH Antigens."

James P. AuBuchon, MD
American Red Cross, Rochester Region
"Use of Indium111 as a Red Cell Label in Survival Studies"

Brooks Jackson, MD
University of Minnesota Hospitals
"Non-Detection of Human Cytomegalovirus DNA in IgM Seropositive Blood Donor Using Spot Hybridization"

Melanie S. Kennedy
Ohio State University Hospitals
"Managerial Role Delineation for Blood Bank Specialists"

Jane M. Rachel, MT(ASCP), MA
Community Blood Center of Greater Kansas City
"Evaluation of a Solid Phase Red Cell Adherence Method for Prospective Platelet Crossmatching"